The difference between Gui Shao Di Huang Wan and Qi Ju Di Huang Wan lies in the composition, efficacy and main treatment. 1. Difference in composition: Gui Shao Di Huang Wan is from Jing Yue Quanshu, this formula is made of Liu Wei Di Huang Wan plus Angelica sinensis and Bai Shao; Qi Ju Di Huang Wan is from Measles Quanshu, this formula is made of Liu Wei Di Huang Wan plus Lycium barbarum and Chrysanthemum. 2. Difference in efficacy: the efficacy of Radix Rehmanniae Praeparata Pill is to nourish the liver and kidney, tonify yin and blood, and clear heat. The efficacy of Qi Ju Di Huang Wan is to nourish the kidney and nourish the liver. 3. Difference in treatments: Rehmanniae Radix Pill is used for treating deficiency of liver and kidney, deficiency of yin and blood, soreness of waist and knees, dizziness, tinnitus, afternoon hot flashes, and dryness of the throat, etc; Qiju Radix Pill is used for treating deficiency of yin in the liver and kidney, dimness of the eyes, blurring of the vision, or dryness of the eyes. The adverse reactions and contraindications of Gui Shao Di Huang Wan and Qi Ju Di Huang Wan are not clear. The drugs must be used under the guidance of a doctor, do not blindly self-medication.