Vesicular foot odor can be cured by itself. Vesicular foot odor is infected by a skin fungus, which may lead to cracking of the skin and affect normal walking if left untreated. Intermittent erosive foot odor is mostly due to sweaty feet, long-term wear of impermeable shoes caused by local bacterial infections, this disease will not be self-healing, medical intervention is needed, if not treated in time, the germs will destroy the protective film of the skin tissue of the feet, so that the skin blisters, peeling, cracking, etc., which will seriously affect the normal walking. Interstitial erosive foot fungus is usually treated with topical medications, such as miconazole, econazole, ketoconazole, etc.; when the area of the rash is large, oral medications, such as terbinafine, itraconazole, etc., can be used. The patient should pay attention to personal hygiene, should wear air permeable shoes, change shoes and socks diligently, fully maintain the feet, shoes and socks clean and dry, do not prolonged immersion of the feet in the water, after washing the feet should be timely to dry between the toes. The patient should follow the doctor’s instructions to standardize the treatment, do not do it on your own, so as not to delay the condition. All of the above drugs should be used under the guidance of a doctor.