Hepatitis B 4 and 5 positive, that is, hepatitis B E antibody positive and hepatitis B core antibody positive, are two normal results, two normal indicators of hepatitis B virus immunology, this situation does not require treatment. This is because a positive hepatitis B E antibody indicates that the hepatitis B virus has been cleared or has stopped replicating through standard treatment or through strong immunity, while a positive core antibody indicates that the body has been or is being infected with the hepatitis B virus. A positive core antibody indicates that the body has been or is being infected with the hepatitis B virus. However, a positive E antibody and core antibody together indicate that the body has entered the recovery phase.