Fiber binding protein 491μg/ml is mildly high and may be caused by bad habits, acute inflammation, liver disease, etc. 1. Bad habits: such as long-term alcoholism, irrational diet, etc. Alcohol can cause damage to liver cells, which in turn leads to liver dysfunction, affecting the liver function. Alcohol can cause damage to liver cells, which in turn leads to liver dysfunction and affects the test results. Patients are advised to stop drinking, eat less animal liver, and have a reasonable diet. 2. Acute inflammatory diseases: such as rheumatoid arthritis, when the body has an acute inflammatory reaction, it will lead to the phenomenon of elevated fiber binding protein. 3. Liver disease: severe fatty liver can lead to liver cell damage, protein synthesis and metabolism abnormalities, fibronectin will be high. At the same time, patients need to undergo liver and gallbladder ultrasound examination for liver fibrosis and cirrhosis. It is recommended that the patient seek timely medical treatment, combined with other indicators and imaging tests, to clarify the diagnosis.