The causes of dry skin like snake skin on the lower legs are usually divided into physiological factors and pathological factors, physiological factors may be related to skin dehydration and dry climate; pathological factors are generally known as ichthyosis in medicine. 1. Physiological factors: if the skin is heavily dehydrated or the climate is too dry, it may cause a large area of skin to appear dry, which may trigger the local appearance of snake skin-like lines, mostly seen in winter. Usually should pay attention to not use too high temperature water bath, the use of moisturizing cream to improve the dry skin. 2. Pathological factors: ichthyosis is mostly a hereditary disease, nutritional deficiencies, environmental dryness and cold as its triggering factors. Mainly manifested as dry skin, flaking and ichthyosis lesions, part of the patient’s skin appearance is snake skin, symptoms can be aggravated in winter, summer relief. The main treatment is to strengthen the skin cleaning and moisturizing, can also use retinoids to improve the skin lesions. There is no unique cause of dry skin on the lower legs like snake skin, after excluding physiological factors, patients are advised to seek medical examination to clarify the cause of the disease.