Thickening of the esophageal tube wall is usually not serious, but it depends on the specific situation. 1. Thickening of the esophageal wall may be related to the patient’s long-term dietary habits, such as eating overheated and irritating foods, which can cause thickening of the esophageal wall. This condition is usually not serious and can be relieved by adjusting the patient’s diet and changing eating habits. 2. Serious: If the patient has not only thickening of esophageal wall, but also has symptoms such as difficulty in swallowing, dyspnea and pain at the sternum, it is considered that there may be pre-cancerous lesions of esophageal cancer, which is more serious and requires the patient to seek medical treatment as soon as possible. It is suggested that patients should go to the hospital to complete the relevant pathological examination to exclude esophageal cancer, and do not use medication on their own to avoid delaying the condition.