The cold hands and feet of newborn babies may be related to physiological factors, or may be caused by iron deficiency anemia and other reasons. 1. Physiological factors: For newborn babies, the development of the thermoregulatory center is still imperfect, and the subcutaneous fat is thin, easy to dissipate heat, there may be cold hands and feet phenomenon. It may also be due to the environment is too cold, do not pay attention to keep warm, resulting in poor blood circulation of nerve endings caused. 2. Iron deficiency anemia: some newborn babies due to iron deficiency anemia, resulting in the brain in a chronic state of hypoxia, may cause cold hands and feet, may also be accompanied by pale, poor appetite and other manifestations. Newborn babies with cold hands and feet may also be related to other factors, such as other types of anemia, insufficient calorie intake, infections, poor local circulation will have cold hands and feet, to rule out physiological factors, it is recommended to seek medical advice as soon as possible, to clarify the cause, the doctor’s guidance on the treatment and conditioning.