Aspergillus singularis is still relatively treatable, being sensitive to a wide range of antibiotics, but of course there are specific components that make it difficult to deal with. Aspergillus singularis is a member of the genus Aspergillus and is widely distributed in nature. Most Aspergillus singularis do not produce β-lactamase and are moderately sensitive to penicillin, sensitive to β-lactam antibiotics, sensitive to aminoglycoside antibiotics such as gentamicin and amikacin, and Aspergillus singularis is also more sensitive to chloramphenicol. Before treatment, we need to do the relevant bacterial drug sensitivity test, choose the appropriate and sensitive antibacterial drug treatment to avoid drug resistance, and need to use drugs under the guidance of physicians. Of course, there are also some special specific components in Aspergillus singularis, which can cause patients to develop sepsis, peritonitis, meningitis and other clinical manifestations, which usually progress more rapidly, and may lead to patients can not be cured.