Do not drink alcohol until at least one week after taking Cephalosporin. Due to the different metabolism speed and ability of alcohol and drugs in each person’s body, after taking Cephalosporin, there is usually a residue of drug ingredients in the body, at least one week before drinking alcohol. Cephalosporin is an antibiotic drug, mainly used for bacterial infections, such as acute tonsillitis, otitis media, pneumonia, etc., and its mechanism of action is to prevent the synthesis of bacterial cell walls. Cephalosporin and alcohol in the body will occur disulfiram-like reaction. Disulfiram-like reaction, also known as drunkenness-like reaction, refers to disulfiram inhibition of acetaldehyde dehydrogenase, blocking the normal metabolism of ethanol, resulting in drinking a small amount of ethanol can also be caused by acetaldehyde intoxication reaction. After using the drug and then drinking alcohol, there will be weakness, dizziness, drowsiness, hallucinations, generalized flushing, headache, nausea, vomiting, blood pressure drop, and even shock and other reactions. Therefore, when using drugs that can cause disulfiram-like reactions, you need to follow the doctor’s instructions.