Low LDL cholesterol often does not have specific symptoms. Low LDL cholesterol is seen in patients with stones and chronic wasting diseases, and in patients with chronic wasting diseases such as tuberculosis and tumors, the symptoms are often those associated with the primary disease. LDL cholesterol is bad cholesterol and is often associated with the development and progression of atherosclerotic disease. For patients with coronary heart disease and cardiovascular diseases, active control of LDL and cholesterol is recommended. For patients with cardiovascular disease and those in the high-risk group, a target LDL cholesterol value of less than 1.8 mmol/L or even 1.4 mmol/L is recommended, and therapeutic lifestyle improvement and medication, and if necessary, surgery and other related treatments are recommended.