Adrenal smooth muscle tumor is relatively rare, usually benign and does not necessarily require surgery. In a few cases, they are malignant and are mainly treated by surgery. For patients who are not suitable for surgical treatment, chemotherapy and radiotherapy can also be chosen for treatment. Adrenal smooth muscle tumor is a kind of tumor disease, the cause is not clear. It may be related to genetic factors, environmental factors, endocrine factors and other reasons. In a few cases, adrenal smooth muscle tumor will affect the release of adrenocorticotropic hormone, and patients may experience electrolyte disorders, abdominal pain, hypertension, metabolic abnormalities, muscle weakness and other symptoms. There are benign and malignant adrenal smooth muscle tumors. If the adrenal smooth muscle tumor is benign and the patient does not show clinical symptoms, it can be observed first. If the tumor is large in size, causing uncomfortable symptoms or malignant, surgical treatment is the mainstay, and the tumor can be directly removed by open adrenal tumor resection, transabdominal laparoscopic adrenal tumor resection and other surgical methods. For malignant adrenal smooth muscle sarcoma, postoperative chemotherapy, radiotherapy and other ways of treatment are also needed. For patients with adrenal smooth muscle tumor, it is recommended to go to regular hospitals and choose the appropriate treatment under the guidance of doctors.