Patients with chronic renal failure often suffer from nausea, vomiting, loss of appetite, abdominal distension and other digestive symptoms, which can be improved through renal replacement therapy and correction of water electrolyte disorders to improve the discomfort of eating and vomiting. The metabolic function of kidney in patients with chronic renal failure is significantly reduced or lost, which can easily lead to metabolic disorders in the body, water and electrolyte disorders and metabolic acidosis, etc. Some patients may also have gastrointestinal mucous membrane damage or ulcer hemorrhage, which can be manifested as nausea, vomiting, loss of appetite, abdominal distension and other symptoms. Patients with chronic renal failure can generally improve their condition through renal replacement therapy such as hemodialysis, peritoneal dialysis, etc.; they also need to actively correct the water electrolyte disorders and metabolic acidosis, such as taking sodium bicarbonate, sevelamer carbonate, calcium carbonate, etc. as prescribed by the doctor to improve the discomfort of nausea and vomiting. It is recommended that patients with chronic renal failure should seek medical treatment in time and under the guidance of professional doctors.