The most common cause of positive urine protein is nephritis, to exclude the influence of physiological factors. Under normal circumstances, the protein in urine is negative during routine urine examination, if it appears positive, it is abnormal. The most common is suffering from a variety of nephritis, such as chronic nephritis, acute nephritis and secondary nephritis, such as purpura nephritis, lupus nephritis, hepatitis B virus-related nephritis, etc. It is necessary to improve the anti-nuclear antibody profile, virus-related and other related tests. At the same time, positive urine protein, which is not in large amount, should also exclude the influence of certain physiological factors. The physiological factors mentioned here mainly refer to exposure to heat sources, exertion, staying up late, and strenuous exercise. These factors can cause a temporary increase in the permeability of the filtration membrane of the kidney, and a small amount of protein will leak out from here, which can be detected in the urine routine. This condition is a physiological factor, which will basically improve after removal and does not require special treatment.