High insulin and high blood glucose may be due to the presence of insulin resistance, most often seen in pre-diabetes or diabetes. Insulin resistance is the failure of a certain amount of insulin to exert the appropriate hypoglycemic effect. When insulin resistance occurs in patients, leading to a decrease in insulin action, patients develop abnormal glucose metabolism, and the body promotes insulin secretion in order to control elevated blood glucose, leading to hyperinsulinemia. Therefore, high insulin and high blood glucose are mostly seen in patients with prediabetes or diabetes. It is recommended to improve the relevant examination. High insulin and high blood glucose are recommended to consult a doctor in time, and be treated positively after a clear diagnosis.