The symptoms of hematoporphyrin are as follows: 1, skin photosensitivity: manifested as pins and needles, burning sensation and significant pain in the epidermis of sun-exposed areas, or the formation of blisters, vesicles, which can progress to scarring and deformity after breaking. 2, sensory and motor neuropathy: can appear as limb pain, numbness, abnormal sensation, motor weakness, and in severe cases, tetraplegia, respiratory muscle weakness, and even respiratory failure. 3, acute abdominal pain: It is a common manifestation, the pain is severe and persistent without obvious localization, and can be accompanied by spasm, abdominal distension, nausea, vomiting, constipation, and even intestinal obstruction.4. Autonomic nerve involvement: it can manifest as tachycardia, increased blood pressure, restlessness, tremor.5. Neuropsychiatric system involvement: it can manifest as dizziness, insomnia, anxiety, restlessness, hallucinations, emotional indifference, depression, fear and altered consciousness, hypothalamic involvement After hypothalamic involvement can cause hyponatremia, leading to seizures.6. Other manifestations: severe patients can develop hemolysis, leading to anemia, increased transaminases, and brownish-red urine during acute seizures.