What happens when uric acid is 600 μmol/L or more

Uric acid 600μmol/L belongs to high uric acid. Elevated uric acid is related to decreased uric acid excretion (renal insufficiency, diabetes, etc.) or increased production (excessive purine intake, erythrocytosis, multiple myeloma, genetic factors, etc.). 1. The normal value of uric acid is 150~416μmol/L for men and 89~357μmol/L for women. However, as women age, the value of uric acid will rise after the decrease of estrogen level, but it is usually lower than 420μmol/L. If the level of fasting blood uric acid is greater than 420μmol/L in the two times of non-same day under the normal purine diet state, then the diagnosis can be regarded as hyperuricemia. 2. Elevated uric acid is associated with low excretion and excessive production of uric acid. (1) Excessive excretion: common in renal insufficiency, diabetes mellitus, dyslipidemia and so on. Renal insufficiency, purine exclusion obstacles; diabetes to hyperglycemia damage to renal function, thus leading to reduced uric acid excretion; lipid metabolism disorders so that lipid increase, increased lipids in the body ketone body increase, the renal tubule of uric acid excretion by the competitive inhibition of uric acid excretion is reduced. (2) Increased production: eating more purine-containing food, such as: seafood, animal offal, beer, etc.; inborn purine metabolism abnormality disorder; secondary causes such as erythrocytosis, multiple myeloma, strenuous exercise. In summary, uric acid 600μmol / L should be timely hospital consultation, under the guidance of the physician to improve the relevant examination, a clear diagnosis and treatment.