The non-invasive DNA report is mainly categorized into high risk, critical risk and low risk, and the incidence of Down syndrome can be determined according to the risk level, which has to be interpreted by the doctor.
1. Low risk: If the report indicates a low risk, the incidence of Down’s syndrome is usually very low.
2. High risk or critical risk: Compared to low risk, if the report indicates high risk or critical risk, the risk of Down syndrome is higher, and further amniocentesis is required to obtain fetal cells from the amniotic fluid for more accurate karyotyping and further diagnosis of Down syndrome.
In addition, regardless of whether the non-invasive DNA is high-risk, critical-risk or low-risk, it is still necessary to undergo regular labor and delivery tests at a later stage, including 4D ultrasound to rule out fetal structural malformations, and glucose tolerance screening for gestational diabetes mellitus.