Sensitive glans refers to the high sensitivity of glans, slight stimulation can easily induce erection and ejaculation, etc. The methods of glans desensitization include oral medication, local anesthetics, behavioral therapy, and surgical treatment. 1. Oral medication: patients with glans sensitivity can be treated with Sertraline, Fluoxetine, Dapoxetine Hydrochloride and other medications orally under the guidance of a doctor. All the above drugs need to pay attention to the side effects and adverse reactions of drugs, please use the above drugs under the guidance of a doctor. 2. Local anesthetics: patients with sensitive glans can also use local topical drugs, such as lidocaine gel, to reduce glans sensitivity. All the above drugs need to pay attention to the side effects and adverse reactions of drugs, please use the above drugs under the guidance of a doctor. 3. Behavioral therapy: patients with sensitive glans can also use condoms for behavioral therapy during sex, as well as stopping method, squeezing method, etc., to reduce glans sensitivity. 4. Surgical treatment: For patients whose glans sensitivity is not obvious with medication or caused by the long prepuce, surgical treatment can be carried out through dorsal penile nerve blocking surgery, circumcision and so on. It is recommended that patients strictly follow the doctor’s instructions to correctly use medication, do not change the dose of drugs or private abuse of drugs, pay attention to the monitoring of the condition in life, regular review and so on.