Shingles is caused by varicella-zoster virus infection. Treatment of herpes zoster may consider medication, physical therapy, etc. 1.Medication: (1) Antiviral drugs: commonly used systemic antiviral drugs include acyclovir, vasiclovir, famciclovir and so on. They can reduce the replication of virus and promote the recovery of the disease. (2) Analgesic treatment: for mild to moderate pain, drugs such as acetaminophen can be considered. For moderate pain, consider gabapentin, pregabalin, etc. For severe acute pain during shingles, drugs such as Pregabalin combined with oxycodone can be considered. (3) Other medications: Vitamin B1 and vitamin B12 are commonly used to relieve nerve inflammation and nerve pain. When the blisters are unbroken, topical glycerine lotion and acyclovir cream can be used to promote skin drying as well as anti-inflammatory; after herpes breakout, 1:5000 furacilin solution can be used as wet compresses, and 2% mupirocin ointment can be used externally after the lesions are dry. 2. Physical therapy: helium-neon laser, infrared and other local irradiation can be considered to promote the blisters scab, relieve pain. When shingles appears, you should seek medical treatment in time and follow the doctor’s instructions. The specific dosage and usage of the above medicines should follow the doctor’s instructions, and should not be self-medicated to avoid adverse reactions.