The HPV vaccine cannot be given during menstruation, because during menstruation, a woman will show a decrease in her body’s resistance, and if the vaccine is given again at this time, there is a risk of fever, or increased local redness and pain. The vaccine can be given after the menstrual period is cleared, because this vaccine can be given a week earlier or a week later without any relationship. So if it is the time when you have your period and it is exactly the time when you should have the vaccine, you can wait until after your period clears to have the injection, and it will have no effect on the efficacy of the drug and the immune effect it produces.