The self-development history of nitroglycerin The Nobel Prize is known as the world’s most famous and authoritative scientific award. So do you know what is the greatest contribution of Mr. Nobel as the founder of the Nobel Prize? That is “dynamite”, the main component of which is nitroglycerin. So how is nitroglycerin in clinical use? In the nineteenth century, a doctor named Brenton’s Royal College of Physicians discovered a substance called amyl nitrite, which can relieve angina and can lower blood pressure. In 1879, William Merrell of Westminster Hospital in London, England, suggested that diluting nitroglycerin would convert it into a safer substance that could be used to treat angina pectoris, which is the precursor to the nitroglycerin tablets now commonly used. How to use nitroglycerin as a “life-saving drug”? The most common use of nitroglycerin is sublingual, 0.5mg (1 tablet) / time, if angina is not relieved, after 5 minutes can be used again, generally not more than 3 times in a row, the total daily dose is generally not more than 2mg. because nitroglycerin in addition to dilate the coronary arteries, relieve angina, but also to lower blood pressure, so it is recommended that patients take nitroglycerin in a sitting, semi-lying, lying or squatting position, in order to prevent hypotension and fainting. It is recommended that patients should take nitroglycerin in a sitting, semi-lying, lying or squatting position to prevent fainting due to hypotension and fall. Nitroglycerin is often used in emergencies as a medicine to prevent angina pectoris, so it is important to store nitroglycerin tablets properly. The correct method of storage should be to keep the drug in a small, airtight brown glass bottle, protected from sunlight. The shelf life of nitroglycerin is about one year, but the expiration date of the medication may be shortened by body temperature if it is carried around for a long time, so it should be replaced once in about 3 months.