39 Women of advanced age who are pregnant should pay attention to a good pre-pregnancy examination, regular pregnancy checkups after pregnancy, attention to rest and nutrition. 1. Pre-pregnancy examination: Before pregnancy, attention should be paid to check whether there are gynecological diseases and other systemic diseases, such as hypertension, hyperthyroidism, diabetes, etc. If you have these diseases, you should follow the doctor’s advice and treat them as early as possible, and you should also have regular checkups after pregnancy. 2. Regular pregnancy checkups:39 Pregnant women of advanced age should be advised to undergo chorionic villus biopsy under ultrasound guidance in early pregnancy to check for chromosomal disorders in the fetus. When prenatal diagnosis is not carried out in early pregnancy, pregnant women can also pass amniocentesis in mid-pregnancy to rule out some fetal diseases in chromosomes or genes. 3. Pay attention to rest: Pregnant women are relatively old and their resistance is poor during pregnancy, so they should ensure sufficient sleep and rest. If the rest is not good, the pregnant woman will be fatigued and have poor immunity, which is not conducive to the normal development of the fetus. 4. Ensure nutrition: It is recommended to have balanced nutrition and eat more fresh vegetables and fruits.