Globally, the incidence of liver cancer ranks sixth among malignant tumors, but it ranks third in terms of deaths. China accounts for 53% of the world’s incidence and deaths, which means that the number of liver cancer patients in China is more than half of the world’s incidence and deaths. In China, liver cancer is the third most common malignant tumor, after lung cancer and gastric cancer, but the second deadliest, after lung cancer. In 2008, the third national retrospective survey on causes of death organized by the Ministry of Health found that the mortality rate of liver cancer was on the rise, and the mortality rate of liver cancer ranked second after lung cancer in urban areas, but was higher than lung cancer in rural areas, ranking first. In terms of age, liver cancer ranks first among causes of death in the 45-64 age group for men and 45-64 age group for women, and this age group is all middle-aged and young people. In China, more than 80% of liver cancers are detected in late stages, but in Japan, 80% are in early stages. The five-year survival rate after treatment of early-stage liver cancer can reach 50%, and if treated in our hospital, the cost is about 50,000 yuan (if it is suitable for radiofrequency, it may not be 50,000 yuan, but 20,000 yuan will do), but if it is advanced liver cancer, the five-year survival rate is only 5%, and the cost of his treatment is usually not less than 200,000 yuan, which results in poor results and high costs. Why is Japan able to detect so many early stage liver cancers? First, the state is responsible for the cost of medical checkups for all high-risk people, and the nation is highly aware of health and follows the rules to go for medical checkups. We all call for regular review of hepatitis B carriers, but not many people listen, and people don’t follow the rules. In Japan, for example, the state stipulates that if you have hepatitis B major and minor triplets, you have to have a medical checkup once every six months or once a year, and when it’s your turn, you can go for a medical checkup that day without working, so all people are guaranteed to go for a medical checkup. But in China, 20% of hepatitis B carriers can comply with the doctor’s orders to go to regular medical checkups is very good. So we should also make it mandatory for people with a history of hepatitis (previous hepatitis B infection, hepatitis C infection) or cirrhosis to have a liver checkup (including a liver ultrasound and a blood test for alpha-fetoprotein AFP) every six months, because the chance of getting liver cancer is two hundred times higher in people with HBV infection over the age of 40 than in normal people.