Impetigo is red and swollen is recommended to be treated by medication, patients should pay attention to keep the skin clean and appropriate isolation, if necessary, plasma transfusion and intravenous gammaglobulin treatment. 1. Drug treatment: (1) Topical medication: for patients with unbroken pustules, 10% glycerite lotion can be used, and when the pustules are large, the pustules can be extracted. For lesions with large scope and much exudation, cold wet compresses such as 0.1% ethacridine lactate solution or 1:5000 potassium permanganate solution can be used. Antibiotics such as mupirocin ointment and fusidic acid cream can also be used. (2) Oral medication: Penicillin or cephalosporin is preferred for systemic treatment. Clindamycin, fusidic acid or vancomycin can also be used according to the patient’s condition. 2. At the same time, pay attention to the patient’s water and electrolyte balance, and transfuse plasma and human immunoglobulin (mainly refers to the immunoglobulin fraction extracted from fresh and healthy plasma, which is mainly used for preventing infections of pathogenic microorganisms and improving immunity) if necessary for those with serious conditions. If you need to use drugs, it is recommended to use them under the guidance of a doctor, do not use them without authorization.