Frozen section pathological diagnosis (referred to as frozen) is made by rapidly freezing the cut lesion tissue in a frozen section machine and making a pathological diagnosis quickly by a pathologist. The patient usually waits on the operating table, which takes about 30 minutes, and after the diagnosis is returned, the surgeon decides whether to further treat the patient surgically. Through freezing, the benignity and malignancy of the tumor can be determined to decide the surgical plan; the spread of malignant tumor can be understood, including whether the tumor infiltrates adjacent tissues and whether there is regional lymph node metastasis. It can also determine whether there is residual surgical cut edge; it can determine what kind of tissues are removed, such as parathyroid glands, fallopian tubes, ectopic tissues, etc. However, frozen diagnosis is not the solution to all pathological diagnostic problems, and its diagnostic accuracy is lower than that of conventional paraffin sections. Due to the limitation of intraoperative sampling of lesion tissues, the formation of ice crystals during the freezing process which affects the quality of the film, as well as the special processing of tissues and the time constraint of reading the film for diagnosis, frozen sections cannot achieve the precise effect of conventional paraffin sections, so that the frozen report may sometimes be inconsistent with the conventional report, and in some cases can only provide the surgeon with a “A more accurate diagnosis depends on conventional paraffin sections. Frozen diagnosis may require the surgeon to send the tissue multiple times and prolong the diagnostic time. Frozen diagnosis requires considerable experience and the ability of the pathologist to make rapid decisions under pressure, as well as recognition of the limitations of this method. Frozen diagnosis is relatively more technically demanding and carries greater responsibility. The possibility of missed or misdiagnosis due to freezing means that there is a certain risk for the patient. Therefore, there are situations in which icing should be used with caution or contraindicated, such as in cases involving amputation and other potentially disabling radical surgical resection of the specimen. In patients requiring such surgical treatment, the nature of the lesion should be determined by routine biopsy prior to surgery. In some cases, it is contraindicated: in cases of suspected malignant lymphoma, because the pathologic diagnosis of lymphoma by frozen section (cryo) is made by rapidly freezing the excised lesion in a frozen section machine and making a pathologic diagnosis by a pathologist quickly. The patient usually waits on the operating table, which takes about 30 minutes, and after the diagnosis is returned, the surgeon decides whether to further treat the patient surgically. Through freezing, the benignity and malignancy of the tumor can be determined to decide the surgical plan; the spread of malignant tumor can be understood, including whether the tumor infiltrates adjacent tissues and whether there is regional lymph node metastasis. It can also determine whether there is residual surgical cut edge; it can determine what kind of tissues are removed, such as parathyroid glands, fallopian tubes, ectopic tissues, etc. However, frozen diagnosis is not the solution to all pathological diagnostic problems, and its diagnostic accuracy is lower than that of conventional paraffin sections. Due to the limitation of intraoperative sampling of lesion tissues, the formation of ice crystals during the freezing process which affects the quality of the film, as well as the special processing of tissues and the time constraint of reading the film for diagnosis, frozen sections cannot achieve the precise effect of conventional paraffin sections, so that the frozen report may sometimes be inconsistent with the conventional report, and in some cases can only provide the surgeon with a “A more accurate diagnosis depends on conventional paraffin sections. Frozen diagnosis may require the surgeon to send the tissue multiple times and prolong the diagnostic time. Frozen diagnosis requires considerable experience and the ability of the pathologist to make rapid decisions under pressure, as well as recognition of the limitations of this method. Frozen diagnosis is relatively more technically demanding and carries greater responsibility. The possibility of missed or misdiagnosis due to freezing means that there is a certain risk for the patient. Therefore, there are situations in which icing should be used with caution or contraindicated, such as in cases involving amputation and other potentially disabling radical surgical resection of the specimen. In patients requiring such surgical treatment, the nature of the lesion should be determined by routine biopsy prior to surgery. In some cases, it is contraindicated: in suspected malignant lymphomas, because the diagnosis of lymphoma is relatively complex and the effect of frozen sections on antigens may interfere with paraffin results; in specimens that are too small (0.2 cm in length), making production difficult and interfering with routine pathologic diagnosis; in those with easy access to routine preoperative biopsy; in adipose tissue, calcified tissue, and bone tissue; in soft tissue tumors that need to be judged as benign or malignant based on karyotype counts Soft tissue tumors, such as uterine smooth muscle tumors and soft tissue sarcomas; tumors that are mainly based on the biological behavior of the tumor but cannot be judged on the basis of tissue morphology, such as thyroid follicular carcinoma; specimens that are known to be infectious (such as tuberculosis, viral hepatitis, AIDS, etc.). Pathological diagnosis requires initial consultation by the attending physician and review by a superior physician. It has been popularized in tertiary hospitals. Only some secondary hospitals have carried out this program. The diagnosis is relatively complicated, the effect of frozen section on antigen may interfere with paraffin results; too small specimens (0.2cm in length and diameter of the specimen) make the production difficult and affect the routine pathological diagnosis; easy to perform routine biopsy before surgery; fatty tissue, calcified tissue and bone tissue; soft tissue tumors that need to be judged as benign or malignant based on nuclear splitting image count, such as uterine smooth muscle tumor, soft tissue sarcoma; mainly based on the tumor’s Tumors that cannot be judged as benign or malignant based mainly on the biological behavior of the tumor but not on the tissue morphology, such as follicular carcinoma of the thyroid gland; specimens known to be infectious (such as tuberculosis, viral hepatitis, AIDS, etc.). The pathological diagnosis requires the initial diagnosis by the h attending physician and review by a superior physician. It has been popularized in tertiary hospitals. Only some secondary hospitals have carried out this program.