Ultrasound endoscopes have different roles to play, and there is no such thing as which one is better. For endoscopic examination found in the gastrointestinal tract submucosal swelling, ordinary gastroscopy can only see the swelling and the surface of the lesion, can not determine its nature. It is necessary to use ultrasound endoscopy to scan the wall of the digestive tract or neighboring organs, and it is feasible to do pathological examination by puncture, so as to clarify the location and nature of the source of the mass. Ultrasonic endoscopy with a large probe can make a complete determination of a large mass, clarify the relationship between its source and adjacent organs, as well as the relationship between vascular supply and support, and whether it is suitable for endoscopic resection, etc. It can be used for the diagnosis of pancreatic tumors, abdominal masses and other visceral diseases. Because of the narrow lumen of the esophagus, the large probe ultrasonic endoscopy has limitations in determining smaller submucosal masses, so for smaller lesions, the small probe is more advantageous for determining the source of the lesion, which can help to diagnose diseases such as lipomas and smooth muscle tumors. The size of the ultrasonic endoscopy probe has its own advantages and disadvantages, suitable for different causes of disease, there is no one better than the other.