Urotropine has some efficacy in halitosis, which can relieve the symptoms, but the efficacy is not good for patients with severe halitosis, while the drug can not achieve the goal of eradicating halitosis. Fox odor, also known as armpit odor, the pathogenesis is not yet clear, may be related to genetic factors, the production of its odor is closely related to the sweat secreted by the sweat glands. If the armpits secrete a large amount of sweat for a long time, bacteria form short-chain fatty acids and ammonia with a special odor by decomposing the organic matter in the sweat, thus leading to bad breath. Urotropine solution has antiseptic, antibacterial as well as antiperspirant effects, which can inhibit the secretion of sweat glands to a certain extent and kill the bacteria in the armpits, resulting in the relief and alleviation of the odor of the fox, but after discontinuing the medication, the functioning of the sweat glands will return to its original level, and the bacteria will re-parasitize and multiply, and the odor of the fox will come back. The use of the drug is prohibited for those who are allergic to the drug urotropin or those who have localized breakouts. In terms of the treatment of halitosis, patients with mild symptoms usually do not need medication, and can be relieved by changing clothes and bathing frequently; they can also follow the doctor’s instructions to apply local medication (such as 2%~4% formaldehyde solution, 20% aluminum chloride anhydrous ethanol solution, etc.) to reduce the symptoms; for those with severe conditions, they can be improved by applying botulinum toxin injections, laser treatment or surgical treatments under the direction of the doctor. The efficacy of urotropin is limited in severe cases of halitosis. Meanwhile, the use of urotropin solution or other medicines alone cannot completely cure halitosis, and it is recommended that patients choose the appropriate way to treat the disease under the guidance of a doctor.