Enlarged tonsils on one side and normal on the other may be congenital or caused by unilateral tonsil disease. If unilateral tonsil inflammation, anti-inflammatory treatment is needed, and if there are tonsil neoplasm or tonsil swelling, surgical removal is needed. It is recommended to go to the ear, nose and throat department of the hospital for professional diagnosis and treatment. 1. Unilateral tonsil inflammation: When there is unilateral tonsil inflammation, it will cause unilateral tonsil enlargement, the other side is normal, the situation is serious, there will also be purulent secretion around the tonsils, you can take anti-inflammatory drugs such as cefaclor, amoxicillin and so on under the guidance of the doctor. Patients with a history of drug allergy are prohibited. 2. Tonsillar neoplasm, tonsillar swelling: tonsillar neoplasm or tonsillar swelling will also appear one side of the tonsil is enlarged, one side is normal. Under the guidance of the doctor, surgical resection such as one side of the tonsil lesion excision, one side of the tonsil swelling excision, etc., to alleviate the situation. When there is an enlargement of one side of the tonsils and one side is normal, you can go to the ENT department to clarify the exact cause and deal with it actively.