Treatments for mature pimples (medically known as acne) include sterile acne needle puncture, medication, and laser treatment. 1. Acne pimple: Usually there are whiteheads coming out of a ripe pimple, which will fall off on its own if left untreated. You can also use a sterile acne needle to pick the pimple, pus discharge, can promote the rapid elimination of pimples, but need to pay attention to prevent infection. 2. Medication: If there are local symptoms of redness, swelling and pain, you can use topical retinoic acid drugs, such as retinoic acid ointment, adapalene gel, etc., which can promote the elimination of pimples and also improve the symptoms; for those who have serious inflammation symptoms, oral antibiotic treatment, such as minocycline, doxycycline, etc. 3. Laser treatment: If the acne is more, the area is bigger, then it can be treated by pulsed laser to eliminate the acne. It is recommended that patients according to their own situation, to the regular hospital dermatology clinic, follow the doctor’s instructions for treatment, under the guidance of the doctor reasonable use of drugs, not blindly self-medication. Normally pay attention to skin hygiene, avoid secondary infection.