Low back pain after sleeping for a long time may be caused by poor sleeping environment, lumbar myofasciitis, herniated disc and other factors, which can be treated with medicines such as meloxicam, improvement of sleeping environment, surgical treatment and so on, and there is no fastest way to relieve the pain in general. 1. Poor sleeping environment: If the patient’s sleeping environment is cold and damp, and the mattress is too soft, it will lead to the lumbar area being cooled or the lumbar area being unsupported, which in turn will cause lumbar pain after sleeping for a long time. Patients can improve relief by replacing hard bed boards and keeping the lumbar area warm. 2. Lumbar fasciitis: If the patient sleeps for a long time with back pain, it may be caused by lumbar fasciitis, which can be relieved by taking non-steroidal anti-inflammatory and analgesic drugs, such as meloxicam. 3. Lumbar disc herniation: If the patient has a lumbar disc herniation, it may be aggravated by sleeping in a bad posture or a soft mattress, and the patient will wake up with back pain. Patients can take nutritive nerve drugs, such as methylcobalamin for improvement, and surgery should be taken if necessary. There are many factors associated with prolonged sleep and low back pain, patients should go to the hospital in time and the above drugs should be taken under the guidance of a physician.