Callus is the common name, clinically known as callus, feet long callus, is due to long-term contact friction, resulting in local keratin keratinization hyperkeratosis, thickening caused by the general treatment, medication (such as Vitamin A acid, etc.), physical therapy, etc., to remove it. 1. General treatment: patients should protect the skin of the feet to avoid friction damage and aggravation of the condition. In addition, patients can soak their feet in hot water, and when the lesions are softened, the cuticle will be peeled off under the operation of the doctor, but it should be noted that do not operate by yourself to avoid infection. 2. Medication: patients can also follow the doctor’s instructions to use exfoliators, such as retinoic acid, salicylic acid, etc., to soften the thickening of the stratum corneum. 3. Physical therapy: patients can also choose liquid nitrogen cryotherapy to remove excessive growth of the stratum corneum. Calluses on the feet recommend that patients go to the hospital in a timely manner, under the guidance of the doctor standardized treatment.