If a patient is taking both Irbesartan and Felodipine to control blood pressure and finds that the blood pressure decreases, then only one medication can be taken to control blood pressure. Irbesartan and Felodipine are antihypertensive drugs with different pathways of action, they can be used together for better control of blood pressure, but after the combination of blood pressure is found to decrease, it is recommended to adjust the drug program. Long-term low blood pressure is detrimental to the patient’s normal life and may be life-threatening, so it is recommended that the patient consult the cardiology department of the hospital to adjust the use of medication. Because in the process of adjusting the medication, there may be a rise in blood pressure after stopping the medication, so it is necessary to monitor the patient’s vital signs to prevent the adverse effects of increased blood pressure. Self-discontinuation of medication is not recommended. The use and adjustment of hypertension medication is a professional medical practice and is recommended to be done under the guidance of a physician.