The severity of 3 plus urine crystals lies in the etiology, the results of the test and the patient’s symptoms. The cause of a high urine crystallization test may be related to diet, pathologic factors, and pharmacologic factors. For the disease caused by increased urine crystals may be more serious. 1. Dietary factors: for example, eating too much high purine food, high purine food, including seafood, chicken breast, animal offal, etc., because of the increase of uric acid in the blood, the urine will appear uric acid crystals, this cause of urinary crystals is generally physiological, will not be serious. 2. Pathological factors: if the patient suffers from urinary stones, acute severe hepatitis, leukemia and other diseases, there may be leucine and tyrosine crystals in the urine, these causes of urinary crystals 3 plus is more serious. 3. medicinal factors: if the patient took sulfonamide drugs, such as compound sulfadiazine tablets, compound sulfamethoxazole tablets and so on resulting in high urine crystallization test results, after stopping the drug or drink more water will generally improve, usually not serious. Urine crystals 3 plus patients to actively seek medical attention, patients do not self-medication, to avoid adverse results.