Pimples around the mouth in boys are commonly associated with acne and can be removed by applying medications, oral medications, and physical therapy. Acne around the mouth in boys may be caused by increased secretion of androgens, excessive sebum production, and clogging of pores. If the acne is relatively small and the symptoms are mild, the treatment is based on topical medication, which can be applied topically to the affected area with retinoic acid cream, adapalene gel, azelaic acid, fusidic acid ointment and so on. If the symptoms are serious, systematic treatment, oral doxycycline, isotretinoin, anti-androgen drugs (spironolactone). If necessary, combined with physical therapy such as blue light or red light treatment. If the situation of acne around the mouth of boys, it is recommended to go to the hospital in time, the drug needs to be used under the guidance of the doctor.