It is not possible to generalize whether or not staying up late will cause acne. If you stay up late only occasionally, you will not usually get acne. If it is a long time frequently stay up late, the phenomenon of acne may occur. If only occasionally stay up late, and their own physical fitness, body immunity and resistance are relatively strong, usually does not appear to have acne phenomenon, do not have to be overly worried, but need to pay attention to regular work and rest, to ensure that sleep is sufficient to avoid staying up late. If it is a long period of frequent late night, easy to lead to body resistance and immunity to reduce, but also easy to cause endocrine disorders, resulting in increased sebaceous secretion, resulting in sebaceous gland ducts blocked, conducive to the growth and reproduction of parasitic bacteria in the hair follicles, which may lead to long acne. In short, stay up late for human health is not good, especially long-term stay up late, not only may cause acne, but also may affect the health, therefore, should try to avoid staying up late. If you experience discomfort, it is recommended that you seek medical attention as soon as possible.