The contraindications of betel nut are still unclear. Betel nut is categorized into “chewing betel nut” and “medicinal betel nut”, “chewing betel nut” is carcinogenic, and chewing betel nut for a long period of time may cause side effects such as popping, pain and increased risk of oral diseases. Chewing betel nut has carcinogenic risk and long-term chewing of betel nut may cause side effects such as joint popping, pain and increased risk of oral diseases; while medicinal use of betel nut is suitable for patients with indications of using betel nut. Betel nut is bitter, pungent, warm and belongs to the stomach and large intestine meridians. It has the efficacy of killing worms, eliminating stagnation, promoting the flow of Qi, inducing diuresis and stopping malaria. Betel nut can be used to treat tapeworm disease, ascariasis, ginger worm disease, abdominal pain caused by worm accumulation, diarrhea (diarrhea caused by stagnation of food and drink), acute and severe pain (discomfort in the lower abdomen, wanting to defecate very much, and feeling of incomplete defecation after defecation), edema and foot fungus, malaria, and so on. In daily life, some people like to chew betel nut products to eat, but long-term consumption of large quantities of betel nut or betel nut products on the human body is harmful, will seriously wear teeth, increase the temporomandibular joints weight-bearing, caused by joint popping, pain and other symptoms, but also to increase the risk of oral diseases. There is a fundamental difference between “chewing betel nut” and “medicinal betel nut”. Chewing betel nut used for young fruits, and added with carcinogenic excipients, can cause stimulation and damage to the oral mucosa, resulting in submucosal fibrosis, white spots, mossy lesions, so can not be no time limit, is a large number of unrestricted use; medicinal betel nut use of ripe kernels, and then by the concocted, processed, and generally short-term consumption, suitable for the use of betel nut indications of the patient. It is recommended to reduce the daily chewing of betel nut to maintain oral health, and for patients with indications for the use of betel nut should be used under the guidance of a professional doctor.