Polio vaccine is the polio vaccine, and no fasting is required for polio vaccination, whether the oral or intramuscular route is used. Polio vaccine is a biological agent that helps the body prevent polio, an infectious disease. The doses of polio vaccine currently in use include oral doses and injections, but no matter which dose of polio vaccine is used, fasting is not explicitly required, so fasting is not necessary. Before applying the polio vaccine, it is important to note that the vaccine is contraindicated in people who are allergic to any of the components of the vaccine, people with acute illnesses, acute exacerbations of chronic illnesses, severe chronic illnesses, people with fever, pregnant women, immunodeficiencies, and people with uncontrolled epilepsy or other progressive neurological disorders. Individuals who experience unusual and serious adverse reactions to the polio vaccine should be careful to seek professional medical help.