Vitamin D3 and Osteotriol can both promote calcium absorption, each has its own characteristics and is suitable for different groups of people, and it is impossible to say which one is better. Vitamin D3 is suitable for people without abnormal liver and kidney function, while Osteotriol is more suitable for people with liver and kidney disease. Vitamin D3 is not active in the human body, it needs to go through the liver cell osteoconjugate diol, and then go through the enzyme catalyzed by renal tubular epithelial cells, and finally generate physiologically active osteoconjugate triol. If a person’s liver and kidney function are abnormal, vitamin D3 cannot be converted into biologically active substances, thus losing its effect. Therefore, patients with abnormal liver and kidney function should preferably choose osteotriol. But for ordinary people with normal liver and kidney function, it is better to choose vitamin D3, because osteotriol has an obvious disadvantage that the risk of triggering hypercalcemia is higher than ordinary vitamin D3. Therefore, you can choose vitamin D3 or osteotriol according to your different situations, and it is best to use it scientifically under the guidance of your doctor.