Itchy blisters on the soles of the feet may be caused by fungal infection, eczema, repeated friction and other reasons. 1. Fungal infection: it may be blister-type athlete’s foot caused by fungal infection. Due to wearing shoes with no air permeability, rich sweat glands in the feet, and humid environment, fungal infection may be triggered, and symptoms such as localized whitening of the skin, blisters, itching or peeling of the skin may appear. 2. Eczema: it may be eczema, due to contact with allergic substances, wearing chemical fiber socks or contact with rubber, plastic and other chemicals, which may lead to allergies in the plantar area, usually manifested as small blisters of the size of a pinhead to a grain of rice, accompanied by itching, pain and other symptoms. 3. Repeated friction: Repeated friction may lead to friction blisters on the soles of the feet, which may be accompanied by itching and pain, due to the wearing of ill-fitting shoes, sedentary behavior, prolonged standing and so on. Itchy blisters on the soles of the feet should be treated in a timely manner, and the cause of the blisters should be clarified and treated according to the doctor’s instructions. Pay attention to keep the skin on the soles of the feet dry, do not scratch the skin.