Whether the positivity of items 1, 2, 4 and 5 of hepatitis B five tests is serious or not depends on the patient’s own condition, if he/she is in the recovery period, it is less serious, if he/she is re-infected, it is more serious. Positive items 1, 2, 4 and 5 of the Hepatitis B test are positive for Hepatitis B surface antigen, Hepatitis B surface antibody, Hepatitis B e antibody and Hepatitis B core antibody. This may indicate that the patient is recovering from hepatitis B virus infection, or that the patient has been re-infected with hepatitis B virus after vaccination or recovery from hepatitis B. If the patient is recovering from hepatitis B virus infection, the hepatitis B virus may not be present in the patient’s body. If the patient is in the recovery period, the hepatitis B surface antigen titer is relatively low, surface antibody has been produced, the serological conversion of surface antigen has not yet occurred, but it may be about to occur, at this time, it is a relatively good state of transition, generally is not serious. However, if the patient is re-infected, this time is more serious, and need timely treatment. Patients should under the guidance of a doctor to carry out quantitative DNA testing of hepatitis B virus, to clarify whether there is a state of infection, if the diagnosis is confirmed, it is necessary to carry out timely antiviral and hepatoprotective treatment.