Long-term use of Irbesartan hydrochlorothiazide tablets without contraindications, generally need to be lifelong medication. Irbesartan hydrochlorothiazide tablets are mainly used for the treatment of essential hypertension, essential hypertension, once diagnosed, generally need to be lifelong medication to control blood pressure, can not be discontinued. Irbesartan hydrochlorothiazide tablets common adverse reactions are dizziness, edema, syncope, nausea, vomiting, etc. The drug is contraindicated in mid-pregnancy, lactating women, drug allergy, anuric patients, severe renal impairment, intractable hypokalemia, hypercalcemia, severe hepatic impairment, biliary cirrhosis and cholestasis. Irbesartan hydrochlorothiazide tablets are generally required to take lifelong medication to control blood pressure, strictly follow the doctor’s instructions for medication, in addition to the patient’s daily need for low-salt, low-fat diet, regular monitoring of blood pressure.