Enlarged spleen with normal blood and liver function may be physiologic splenomegaly, or it may be related to some diseases, such as chronic hepatitis and cirrhosis. Splenomegaly can be considered as long as the splenic margin can be touched under the left rib margin, and splenomegaly can be categorized into physiological and pathological. 1. If the blood routine liver function is normal and only the spleen is enlarged, it may be physiologic splenomegaly, which is relatively rare clinically, and is usually not accompanied by splenic hyperfunction; therefore, except for splenomegaly, all other tests are usually normal, and there are no other clinical symptoms. There is no serious harm to the body, so there is no need to worry too much, and regular checkups are sufficient. 2. There are many causes of splenomegaly, although routine liver function is normal, but we can not rule out other diseases, such as acute and chronic hepatitis, cirrhosis, constrictive pericarditis, juvenile rheumatoid arthritis. Splenomegaly blood routine liver function normal can not accurately determine the disease, but also need to combine with the characteristics of the medical history, other test results to make an accurate judgment, it is recommended to clarify the disease under the guidance of a doctor.