Gray nails that nail fungal disease, there is no such thing as the safest treatment for gray nails in the elderly, commonly used clinical treatments for topical medication and systemic medication, can also be surgical extraction of nails, but the damage is large. 1. Topical medication: commonly used for superficial and simple distal damage that does not involve the root of the nail. First, use a knife or nail file to remove as much as possible the diseased nail, and then use 30% glacial acetic acid solution or 3%~5% iodine tincture, can also be used 40% urea ointment sealing package to make the diseased nail softening peeling, and then topical antifungal preparations, such as 8% cyclopiazepine and 5% amorphophallus nail applicator. 2. Systemic drug therapy: Itraconazole, terbinafine, etc., and external drug combination therapy can improve the efficacy. 3. Surgical nail extraction: painful and damaging, less used at present. Elderly gray nail patients should not use their own medicine, should go to the hospital in time, under the guidance of the doctor standardized treatment.