The treatment of feeling aggravated after taking probiotics varies according to its causes, common causes include the drug itself, dosage, personal constitution, etc., the specific disposition should follow the doctor’s advice. 1. The drug itself: when the probiotic preparation there are quality problems, or the use of the expiration date will affect its pharmacological effect, may lead to worsening of the condition after taking the drug. At this time, you can go to the regular medical institutions to re-purchase drugs, standardized use and then observe the efficacy. 2. Dosage: If you don’t use the medicine according to the instructions, such as taking the medicine for too short a period of time or using too little, it may lead to poor efficacy and aggravation of the condition. At this time, you should continue to use the drug for a period of time or follow the doctor’s instructions to adjust the dosage, and then observe its efficacy. 3. Individual constitution: If the user is less sensitive to the selected probiotic, or does not meet the indications of this kind of drug (i.e. intestinal dysfunction caused by intestinal flora imbalance), it may lead to aggravation of the condition after taking the drug. In this case, the treatment should be changed to other drugs under the guidance of the doctor. It should also be noted that probiotic preparations are contraindicated in people who are allergic to them, and the adverse effects are not known. In summary, when the condition worsens after taking probiotics, you should seek medical advice to find out the cause and then adjust the medication accordingly under the guidance of your doctor. Do not blindly judge and dispose of it on your own, so as not to cause adverse consequences.