Taking uric acid-lowering medications can have an impact on your physical exam. Common uric acid-lowering drugs include drugs that reduce uric acid production such as allopurinol and febuxostat, and drugs that promote uric acid excretion such as benzbromarone. Among them, allopurinol is more obvious, may appear leukopenia, thrombocytopenia, anemia and other adverse reactions of the blood system, as well as fever, lymph node swelling, hepatotoxicity, interstitial nephritis and other adverse reactions. Physical examination will routinely check the blood routine, liver and kidney function, etc., if the above adverse reactions will have an impact on the results of the physical examination, if there is no adverse reaction, the impact is not obvious. After taking uric acid-lowering drugs need to follow the doctor’s instructions for regular review, the occurrence of the above situation in the doctor’s guidance in a timely manner to stop the drug or adjust the treatment program, in order to avoid the emergence of serious consequences.