Conservative treatment of advanced pancreatic cancer has a smaller possibility of surviving for 10 years, but active treatment can maximize the survival period. Patients with advanced pancreatic cancer will show obvious emaciation, malnutrition, jaundice, multi-organ failure, etc. This is due to the metastasis and enlargement of the tumor, which invades normal tissues and organs. Especially when advanced pancreatic cancer patients have difficulty in eating, their physical condition will deteriorate sharply in a short period of time. Moreover, if advanced pancreatic cancer cannot be operated, it can be mainly controlled by radiotherapy, chemotherapy and other methods to control the tumor progression, and at the same time, nutritional support, analgesia and other auxiliary means can be given, which can achieve the therapeutic effect of prolonging the survival period and reducing the patient’s pain, but it is difficult for the survival period to reach ten years. Patients with advanced pancreatic cancer need to actively seek medical treatment, do not self-medicate or listen to partial beliefs, and prolong their life cycle and improve their quality of life through standardized treatment.