Survival of 40 years is possible for patients with pancreatic cancer, usually for early-stage patients with a long life expectancy. However, the prognosis of pancreatic cancer patients varies from person to person, with some studies claiming that their 1-year survival rate after diagnosis is only 20-25%. Pancreatic cancer is a malignant tumor of the digestive tract with insidious onset, rapid progression, and extremely poor treatment results and prognosis. Early symptoms of pancreatic cancer are not obvious, and it is easy to lose the best time for treatment because it is mostly in the middle and late stages when it appears conscious symptoms or when it is diagnosed. However, there are still some patients with lesions found in early stage, and through radical resection by surgery, and receiving adjuvant therapy after surgery according to the situation, some patients can achieve clinical cure status, and there is a possibility of survival for 40 years, but the possibility is relatively small. The prognosis of pancreatic cancer is related to the nature of the tumor, the stage (size, infiltration range, metastasis, etc.), the treatment mode, the patient’s own situation and other factors. The prognosis of malignant tumors is usually described by the survival rate of several years after diagnosis, such as 1-year survival rate, 5-year survival rate and so on. The prognosis of pancreatic cancer varies from person to person, and there is no uniform standard or accepted conclusion. Some studies claim that the prognosis of pancreatic cancer is extremely poor, with an overall 5-year survival rate of only about 8%. Other studies claim that the 1-, 2-, and 3-year survival rates after diagnosis of pancreatic cancer are 21.5%, 6.0%, and 4.0%, respectively, with an overall median survival of only 5.5 months. If pancreatic cancer is suspected or diagnosed, it is recommended to go to a regular hospital for evaluation of the condition and follow the doctor’s instructions for treatment to avoid delays.