The difference between gastric cancer and pancreatic cancer lies in the different locations of onset, different clinical manifestations and different treatment methods. 1. Different locations: gastric cancer is a malignant tumor originated from gastric epithelium, while pancreatic cancer is a malignant tumor originated from pancreas. 2. Different clinical manifestations: more than 70% of early gastric cancer is asymptomatic, and conscious symptoms such as epigastric discomfort, acid reflux, belching, early satiety and other non-specific dyspeptic symptoms appear only when the disease develops to a certain degree; the common symptoms of progressive gastric cancer are epigastric pain, loss of appetite and emaciation, vomiting of blood and black stools, and difficulty in swallowing. Clinical manifestations of pancreatic cancer: epigastric pain, fullness and discomfort, jaundice, decreased appetite and emaciation. 3. Different treatment methods: the treatment principle of stomach cancer is mainly based on surgery, followed by chemotherapy, radiotherapy, targeted therapy, traditional Chinese medicine and other therapies. Pancreatic cancer can be considered to be resected first, and for unresectable pancreatic cancer, chemotherapy, radiotherapy, immunotherapy and other comprehensive treatments can be used. There is a big difference between stomach cancer and pancreatic cancer, but the similarity is that both of them need timely detection and timely treatment, so as not to delay the condition.