Sudden increase in menstrual flow at the age of 52 is usually caused by perimenopausal syndrome, uterine fibroids, endometrial cancer and other diseases, which can be treated with medication and surgery as prescribed by the doctor. 1. Perimenopausal syndrome: As women age, ovarian function gradually declines, and sex hormone levels gradually drop, leading to menstrual changes such as a sudden increase or decrease in menstrual flow. First of all, observe and if necessary, follow the doctor’s instruction to use medicines such as medroxyprogesterone acetate tablets and dydrogesterone to treat the disease. 2. Uterine fibroid: it can cause abnormal menstruation, such as sudden increase in menstrual flow and prolonged duration of menstruation, which may be accompanied by increase in vaginal secretion and lower abdominal discomfort. The doctor may prescribe the use of treprostinil acetate and mifepristone to reduce the size of fibroids; for those with heavy bleeding, tranexamic acid may be used; for those with anemia, iron supplements may be used as appropriate. Usually, after menopause, the tumor will shrink and subside, and those who have surgical indications can take surgery to remove the fibroid. 3. Endometrial cancer: It can also cause sudden increase in menstrual flow, accompanied by abnormal vaginal discharge, lower abdominal distension, anemia and other symptoms. It can be treated with surgery after the doctor’s evaluation, and combined with radiotherapy after the surgery. In addition, there are many other causes of sudden increase in menstrual flow in 52-year-old women. Patients are advised to go to the hospital in time to find out the cause of the disease and receive treatment as soon as possible.