Licorice and peony soup should be Paeonia lactiflora and licorice soup. Painful ejaculation belongs to the category of blood semen in traditional Chinese medicine, etc. Clinical treatment with Paeonia lactiflora and Glycyrrhiza glabra soup is not usually used alone to treat this disease, and the specifics should be in accordance with the doctor’s instructions. Paeonia lactiflora and Glycyrrhiza glabra soup is a traditional Chinese medicine formula composed of Paeonia lactiflora and Glycyrrhiza glabra. The formula uses Paeonia lactiflora to nourish blood and benefit the yin, and to ease the urgency and relieve the pain (to relieve the urgent pain symptoms); Glycyrrhiza glabra has the efficacy of nourishing the middle Jiaozhong and benefiting the vital energy (treating the deficiency of vital energy by nourishing the spleen); the two medicines are combined together to ease the urgency and relieve pain. The two herbs together have the effect of easing the pain and relieving the urgency. They are effective in treating conditions such as deficiency of yin and blood, leg and foot cramps, and abdominal pain. From the point of view of clinical application, Paeoniae Radix Glycyrrhizae Tang is generally not used alone for the treatment of ejaculatory pain. Adverse reactions, contraindications, and precautions are unclear. The disease is commonly characterized by dampness-heat accumulation (dampness and heat evils accumulate with each other in the body), qi stagnation and blood stasis, and yin deficiency of the liver and kidney, etc. It should be treated with the prescriptions of Longguan Diarrhea and Liver Tang, Shaobuyu Tang, and Liver Tuning Essence, respectively, and may be accompanied by acupuncture, tuina, and psychotherapy. If the patient is not feeling well, it is recommended to consult the doctor in time, improve the relevant examination to clarify the diagnosis and standardize the treatment, and it is not advisable to use medication on one’s own in order to avoid delaying the condition.